Enrichment Faculty Labs

Andrew Lab

The Andrew lab studies molecular diagnostics for bladder and lung cancers, toxic metal carcinogenesis, genetic susceptibility, gene-environment interactions.

Galton Lab

Dr. Galton studies the roles of the iodothyronine deiodinases in the regulation of intracellular thyroid hormone levels and thyroid hormone action during development and in adult mammals. Studies use mice made deficient in the either or both the types 1 and 2 iodothyronine deiodinase.

Guyre Lab

Dr. Guyre collaborates with clinical and basic science research faculty to investigate the mechanisms by which hormones and cytokines interact to regulate the functional activity of white blood cells-- especially monocytes and macrophages.

Lee Lab

Dr. Lee's research focuses on molecular pathogenesis of Parkinson's disease; The laboratory studies the biological function of Parkinson's disease-associated genes using genetic, molecular, cellular, and model organism approaches.

Leiter Lab

Dr. Leiter's lab studies respiratory neurobiology especially in the areas of pH regulation in neurons and astrocytes, central chemosensitivity and comparative aspects of rhythm generation.

Lewis Lab

Dr. Lewis is interested in the study of novel antineoplastic agents and their pharmacokinetics and pharmacodynamics when first given to cancer patients (i.e. first time in man, Phase I studies of new drugs in cancer patients); mechanisms of toxicity of nucleoside analogues and antineoplastic agents to the mitochondrion and ways of ameliorating this toxicity.

Lowrey Lab

Dr. Lowrey studies the role of epigenetics and cell stress signaling in normal and disease-related blood cell production; development of novel pharmacologic therapies for sickle cell disease, thalassemia and leukemia.

Maue Lab

Dr. Maue is interested in cellular and molecular mechanisms underlying neuronal development in the CNS, particularly as related to neurodegenerative diseases; neurotrophin and growth factor actions; regulation of neuronal ion channels and genes; molecular biology; electrophysiology.

North Lab

Dr. North studies neuropeptides in breast cancer, in small-cell carcinoma, and in Alzheimer's disease.

Spaller Lab

The Spaller lab is interested in the discovery and development of cellular probes and therapeutic agents targeting protein-protein interactions; chemical biology; peptide and organic small molecule design and synthesis; chemical libraries for biochemical and cell-based screening; protein biochemistry and biophysical analysis of protein-ligand interactions.

Vincenti Lab

Dr. Vincenti studies the regulation of matrix metalloproteinase gene expression in arthritis and cancer. The major goal of this work is to understand how inflammatory signal transduction activates metalloproteinase transcription.

Wishart Lab

The Wishart lab studies Functional and Structual Magnetic Resonance Imaging: Neurobiological basis of heterogeneity in multiple sclerosis. A hallmark of multiple sclerosis (MS) is its interindividual heterogeneity. Dr. Wishart's research program uses structural and functional MRI and genotyping to discover neurobiological mechanisms of heterogeneity in symptomatology, course and treatment response in MS, with the ultimate aim of improving early, individualized characterization and treatment of the disease.