Itzel Rojas

Postdoctoral Scholar, Tufts University

B.S. University of Arizona
Ph.D. '19, Cancer Biology, Pharmacology and Molecular Therapeutics, Dartmouth College

Obesity and fatty liver are prevented by inhibition of the aryl hydrocarbon receptor in both female and male mice. Moyer BJ, Rojas IY, Kerley-Hamilton JS, Nemani KV, Trask HW, Ringelberg CS, Gimi B, Demidenko E, Tomlinson CR. Nutr Res. 2017 Aug;44:38-50.
Indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors activate the aryl hydrocarbon receptor. Moyer BJ, Rojas IY, Murray IA, Lee S, Hazlett HF, Perdew GH, Tomlinson CR. Toxicol Appl Pharmacol. 2017 May 15;323:74-80.
Inhibition of the aryl hydrocarbon receptor prevents Western diet-induced obesity. Model for AHR activation by kynurenine via oxidized-LDL, TLR2/4, TGFβ, and IDO1. Moyer BJ, Rojas IY, Kerley-Hamilton JS, Hazlett HF, Nemani KV, Trask HW, West RJ, Lupien LE, Collins AJ, Ringelberg CS, Gimi B, Kinlaw WB 3rd, Tomlinson CR. Toxicol Appl Pharmacol. 2016 Jun 1;300:13-24.