Jonathan Kleen

Assistant Professor, University of California, San Francisco

I look at memory circuits in the human brain and how they are affected by epilepsy, and also work on multimodal visualization techniques for seizure localization.

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  • MD '13, Geisel School of Medicine
  • PhD '11, Neuroscience, Dartmouth College

Selected Publications

  • Kleen JK, Scott RC, Holmes GL, Roberts DW, Rundle MM, Testorf M, Lenck-Santini PP, Jobst BC. Hippocampal interictal epileptiform activity disrupts cognition in humans. Neurology. 2013; 81(1):18-24.

  • Kleen JK, Scott RC, Lenck-Santini PP, Holmes GL. Cognitive and Behavioral Co-Morbidities of Epilepsy. In: Noebels JL, Avoli M, Rogawski MA, Olsen RW, Delgado-Escueta AV, editors. Jasper's Basic Mechanisms of the Epilepsies [Internet]. 4th edition. Bethesda (MD): National Center for Biotechnology Information (US); 2012.

  • Kleen JK, Wu EX, Holmes GL, Scott RC, Lenck-Santini PP. Enhanced oscillatory activity in the hippocampal-prefrontal network is related to short-term memory function after early-life seizures. J Neurosci. 2011; 31(43):15397-406.

  • Kleen JK, Sesqué A, Wu EX, Miller FA, Hernan AE, Holmes GL, Scott RC. Early-life seizures produce lasting alterations in the structure and function of the prefrontal cortex. Epilepsy Behav. 2011; 22(2):214-9.

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