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I use electrophysiology, optogenetics, and advanced optics to study neuromodulation and circuit formation in the developing basal ganglia in the laboratory of Yevgenia Kozorovitskiy at Northwestern University.
Howe, J.R., Li, E.S., Streeter, S.E., Rahme, G.J., Chipumuro, E., Russo, G.B., Litzky, J.F., Hills, L.B., Rodgers, K.R., Skelton, P.D., et al. (2017). MiR-338-3p regulates neuronal maturation and suppresses glioblastoma proliferation. PloS one 12, e0177661.
Williams, M.R., Fricano-Kugler, C.J., Getz, S.A., Skelton, P.D., Lee, J., Rizzuto, C.P., Geller, J.S., Li, M., and Luikart, B.W. (2016). A Retroviral CRISPR-Cas9 System for Cellular Autism-Associated Phenotype Discovery in Developing Neurons. Scientific reports 6, 25611.
Robinson S, Todd TP, Pasternak AR, Luikart BW, Skelton PD, Urban DJ, Bucci DJ. Chemogenetic silencing of neurons in retrosplenial cortex disrupts sensory preconditioning. J Neurosci. 2014 13;34:10982-8.
Skelton PD, Frazel PW, Lee D, Suh H, Luikart BW. (2019). Pten loss results in inappropriate excitatory connectivity. Molecular Psychiatry. Online ahead of print. DOI: 10.1038/s41380-019-0412-6