We study the multicellular interactions between neurons and glia in the brain with a primary focus on the development, plasticity, and regeneration of myelinating oligodendrocytes. Techniques include high-resolution optical imaging in combination with molecular labels, genetic manipulation, and sensors of cellular physiology.
Chapman TW, Olveda GE, Pereira E, and Hill RA. Age and axon-specific forms of cortical remyelination by divergent populations of NG2-glia. bioRxiv (2020) doi.org/10.1101/2020.12.09.414755
Chapman TW and Hill RA. Myelin plasticity in adulthood and aging. Neuroscience Letters. (2020) 134645. PMID: 31765728
Hill RA#, Li AM, and Grutzendler J# Lifelong cortical myelin plasticity and age-related degeneration in the live mammalian brain. Nature Neuroscience. (2018) 21 (5), 683-695 PMID: 29556031, highlighted by Neuron, Nature Reviews Neuroscience and Yale News. #co-corresponding author
Hill RA, Damisah EC, Chen F, Kwan AC, and Grutzendler J. Targeted two-photon chemical apoptotic ablation of defined cell types in vivo. Nature Communications. (2017) 8,15837 PMID: 28621306.