Ryan Soderquist

Post-Doctoral Fellow, Duke University, North Carolina

Education

PhD, '14, Cancer Biology and Molecular Therapeutics, Dartmouth College

Selected Publications

  • Soderquist RS, Danilov AV, Eastman A. Gossypol Increases expression of the pro-apoptotic BH3-only protein NOXA through a novel mechanism involving phospholipase A2, cytoplasmic calcium, and endoplasmic reticulum stress. J Biol Chem. 2014; 289(23):16190-16199.

     

     

  • Soderquist R, Pletnev AA, Danilov AV, Eastman A. The putative BH3 mimetic S1 sensitizes leukemia to ABT-737 by increasing reactive oxygen species, inducing endoplasmic reticulum stress, and upregulating the BH3-only protein NOXA. Apoptosis. 2014; 19(1):201-9.

  • Danilov AV, Soderquist RS, Bates DJ, Eastman A. Toward a cure for chronic lymphocytic leukemia: an attack on multiple fronts. Expert Rev Anticancer Ther. 2013; 13(9):1009-12.

  • Soderquist R, Bates DJ, Danilov AV, Eastman A. Gossypol overcomes stroma-mediated resistance to the BCL2 inhibitor ABT-737 in chronic lymphocytic leukemia cells ex vivo. Leukemia. 2013; 27(11):2262-4.

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Awards

Dartmouth Graduate Student Travel Award, 2014

Best Poster Award, Molecular Therapeutics of Cancer conference, 2013