Sladjana Skopelja-Gardner

Our research aims to identify how innate immune pathways drive the development of autoimmunity and contribute to disease pathogenesis. We are addressing these questions in models of skin sterile inflammation that are relevant to autoimmune diseases such as systemic lupus erythematosus (SLE) and dermatomyositis (DM), as well as in primary human tissues. With the goal to identify novel therapeutic targets, we are investigating the regulation of type I interferon response as well as neutrophil migration and function.