Abigail Goen

Miller lab

Abigail graduated summa cum laude from the University of New Hampshire. Here at Dartmouth, she is in our Cancer Biology program and does translational research on ER+ metastatic breast cancer (MBC). Her research aims to identify and target therapeutic vulnerabilities in the dormant and metastatic setting in an effort to expand the treatment options for patients with ER+/HER2- MBC. One line of inquiry is focused on targeting specific proteins in drug tolerant persister cells that promote fatty acid oxidation, which cells utilize to escape cell death while on adjuvant therapy. Another line of study investigates mutations in ESR1, the gene that codes for the estrogen receptor. She aims to investigate novel therapeutic strategies that target these mutants. Abigail is passionate about outreach and engaging with the community. She enjoys hiking, reading, and local adventures with her husband and three children.  


HB Hinman Box 7936

Selected Publications

  • Hampsch RA, Wells JD, Traphagen NA, McCleery CF, Fields JL, Shee K, Dillon LM, Pooler DB, Lewis LD, Demidenko E, Huang YH, Marotti JD, Goen AE, Kinlaw WB, Miller TW. AMPK Activation by Metformin Promotes Survival of Dormant ER+ Breast Cancer Cells. Clin Cancer Res. 2020 Jul 15;26(14):3707-3719. doi: 10.1158/1078-0432.CCR-20-0269. Epub 2020 Apr 22. PMID: 32321715; PMCID: PMC7367755.