Chenhui Deng

Compton and Godek labs

Chenhui received his B.S. in Biological Science from Nanjing University, Nanjing, China. He works with Dr. Duane Compton and Dr. Kristina Godek in the Department of Biochemistry and Cell Biology. He studies the causes and consequences of aneuploidy during human development using embryonic stem cells and induced pluripotent stem cells as model systems. More specifically, combining quantitative microscopy, live-cell imaging, and biochemical approaches, his thesis research focuses on mechanisms for the low fidelity of chromosome segregation and the pathways that respond to chromosome segregation errors and confer the initial tolerance to aneuploidy in pluripotent embryonic cells. Outside of lab, Chenhui enjoys visiting new places, binge watching TV shows, making and sharing memes, and exploring New England with friends.

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Selected Publications

  • Deng, C., Ya, A., Compton, D.A., Godek, K.M., 2023. A pluripotent developmental state confers a low fidelity of chromosome segregation. Stem Cell Reports 18, 475–488. https://doi.org/10.1016/j.stemcr.2022.12.008 PMID: 36638786. PMCID: PMC9968987. (Featured as the cover in the Feb 2023 issue of Stem Cell Reports)