Bioengineering Faculty

Margaret E. Ackerman, Ph.D.

margaret_ackerman.jpg.png

Margaret Ackerman

Professor of Engineering, and Microbiology and Immunology

Thayer School of Engineering

Office: 119B Cummings Hall


Phone: 603-646-9922

The Ackerman laboratory conducts interdisciplinary research at the interface of biomedical and engineering sciences: developing high throughput tools to evaluate the antibody response in disease states ranging from infection to cancer in order to aid in therapeutic antibody and vaccine design and development, and to understand the protective mechanism of antibodies using approaches grounded in fundamental engineering principles utilizing protein evolution, molecular biology, and mathematical modeling.

Website | Email | PubMed Articles  | Geisel Profile

Britt A. Goods, Ph.D.

britt.jpg

Briff A. Goods, Ph.D.

Assistant Professor of Engineering, and Molecular and Systems Biology

Thayer School of Engineering

Office:   ESCS 121

Phone:  603-646-2368

The Goods Lab solves problems at the intersection of engineering, the immune system, and reproductive health by improving our understanding of biology and by developing tools and systems biology approaches to understand, manipulate, and integrate biological knowledge. The long-term goal of Dr. Goods' research is to improve the lives of people by building a better understanding of the interplay between reproductive health and immunology, and translating those insights into therapeutics, diagnostics, and novel ways of both studying and monitoring reproductive and overall health.

Website | Email PubMed Articles  | Geisel Profile

Karl E. Griswold, Ph.D.

karl_e._griswold.png

Karl Griswold

Professor of Engineering, and Biological Sciences

Office: 128E Cummings Hall

Phone: 603-646-2127


The Griswold research group develops performance-enhanced biomolecules through the application of protein engineering technologies. Current projects are focused on biotherapeutic agents.


Website | Email | PubMed Articles

 | Faculty Profile

Jiwon Lee, Ph.D.

jiwon_lee.jpg

Jiwon Lee

Ralph and Marjorie Crump Assistant Professor of Engineering

Thayer School of Engineering

Office:  ECSC 135J

Phone:  603-646-3485

The Lee Lab studies the dynamics of antibody repertoires in infectious disease, autoimmune disease, and cancer using high-throughput sequencing of B cell transcripts and high-resolution mass spectrometry. The repertoire of antibody molecules circulating in blood or coating mucosal surfaces is the basis for protective immunity, and we employ machine learning frameworks, big data analytics tools, proteomic analytical methods, and data modeling to gain clinically relevant insights regarding protective mechanisms at unprecedented details. Leveraging this knowledge, we aim to design next-generation therapeutics and vaccines precisely tailored to maximize effectiveness in the context of particular diseases and/or patients (i.e. personalized/precision medicine).

Website | Email | PubMed Articles 

Lee R. Lynd, D.E.

lee_lynd.jpg

Lee Lynd

Paul E. / Joan H. Queneau Distinguished Professor in Environmental Engineering Design, and Professor of Biological Sciences

Office: 128D Cummings

Phone: 603-646-2231 


Professor Lynd is an expert on the production of energy from plant biomass and conducts leading research on microbial cellulose utilization. 


Website | Email | PubMed Articles

 | Faculty Profile

Aaron McKenna, Ph.D.

aaron_mckenna.jpg

Aaron McKenna

Assistant Professor of Molecular and Systems Biology

Office:  658 Williamson Translational Research Building

Phone:  603-650-1866

My lab is interested in how cells grow and divide to form complex structures, such as the transformation from the zygote to an adult human or from a transformed cell into a tumor mass. To study these processes, we develop technologies to trace pattern of cell divisions which recovers the lineage of each cell. This information can be combined with other measures of cell state such as single-cell transcriptomic data to develop a rich picture of how choices are made in development and how this process is dysregulated in diseases such as cancer.

Website | Email | PubMed Articles

Kimberley Samkoe, Ph.D.

kimberley_samkoe.jpg

Kimberley Samkoe

Associate Professor of Surgery, and Thayer School of Engineering

Office:  747 Williamson Translational Research Building

Phone:   603-650-7618

Brief research description: My research takes a biological-systems-engineering approach to medical imaging by studying how microscopic molecular information can be interpreted at a macro-scale. My current research interests involve quantitative assessment of in vivo protein expression and signaling using fluorescence molecular imaging. These methodologies have applications in cancer for improving tumor identification, surgical resection, and patient-specific therapeutic monitoring.

Website | Email

Rahul Sarpeshkar, Ph.D.

rahul-sarpeshkarjpg.jpg

Rahul Sarpeshkar

Thomas E Kurtz Professor, Professor of Engineering, Microbiology and Immunology, Physics, Molecular and Systems Biology

Office: 507A Vail

Phone: 603-646-6821


Synthetic analog and digital biological circuits in electri-cigenic and other microbes; Applications of synthetic and systems biology to immunology, infectious disease, and cancer; Precision measurement, electronic circuit modeling, and feedback control of living cells at the fundamental limits set by physics.

Email | 

Geisel Profile

Daniel Schultz, Ph.D.

daniel_schultz.jpg

Daniel Schultz

Assistant Professor of Microbiology and Immunology

Office: 206 Vail

Phone: 603-646-5390

The Schultz lab develops quantitative approaches to study the emergence, operation and optimization of the gene networks that control cell responses in bacteria, with a focus on antibiotic resistance mechanisms. We combine mathematical modeling, bioinformatics, experimental evolution and microfluidics to analyze how the cell controls the expression of resistance genes during drug responses. We strive to guide innovation in clinical therapies by uncovering the selective pressures that shape the evolution of antibiotic resistance in natural environments.

Website | Email | PubMed Articles

 | Geisel Profile

Edward J. Usherwood, Ph.D.

edward_usherwood.png

Edward Usherwood

Professor of Microbiology and Immunology

Office: 608E Borwell

Phone: 603-646-5224


Research in the Usherwood lab focuses on T cell-mediated immune surveillance to virus infections and cancer. We are interested in factors that regulate T cell memory and immune surveillance. A major goal is to exploit these findings to develop novel immunotherapies for cancer and persistent virus infections.

 

Email | PubMed Articles

 | Geisel Profile | Website