Henry N. Higgs

Mammalian cells use actin filaments in a huge number of ways, and we are trying to figure out how cells control when and where specific actin-based structures are made. We use a combination of cellular (live-cell microscopy, fluorescence microscopy, EM, cell-free assays) and biochemical (actin polymerization kinetics, analytical ultracentrifugation, structural analysis) in our research.