Kenneth Mark

Supattapone lab

Graduating from the University of Washington, Kenneth received a B.S. in Biochemistry and minored in both Microbiology and Chemistry. Within the Supattapone laboratory in the Biochemistry and Cell Biology department, Kenneth's research revolves around using CRISPR-Cas9 genome-wide screens to identify novel regulators of organelle biogenesis and degradation. Not much is known about the cell biology of how organelles are made and degraded in a regulated fashion. Kenneth is also interested in answering other fundamental questions in cell biology including how mammalian cell size is regulated. Kenneth is currently President of the Dartmouth Graduate Consulting Group. In his spare time, he enjoys cooking, listening to a lot of podcasts and trying to keep up with the cultural zeitgeist.  

Contact

6036501194

Selected Publications

  • Burke CM, Mark KMK, Walsh DJ, Noble GP, Steele AD, Diack AB, Manson JC, Watts JC, Supattapone S. Identification of a homology-independent linchpin domain controlling mouse and bank vole prion protein conversion. PLoS Pathog. 2020 Sep 8;16(9):e1008875. doi: 10.1371/journal.ppat.1008875. eCollection 2020 Sep.  

    Chidawanyika T, Mark KMK, Supattapone S. A Genome-Wide CRISPR/Cas9 Screen Reveals that Riboflavin Regulates Hydrogen Peroxide Entry into HAP1 Cells. mBio. 2020 Aug 11;11(4):e01704-20. doi: 10.1128/mBio.01704-20.  

    Mark KMK, Varn FS*, Ung MH, Qian F, Cheng C. The E2F4 prognostic signature predicts pathological response to neoadjuvant chemotherapy in breast cancer patients. BMC Cancer. 2017