Xiaofeng Wang

Our work focuses on cancer epigenetics. We are particularly interested in studying a family of chromatin remodeling complexes, which are frequently mutated in a variety of human cancers. Our work is aimed to understand how these mutations cause cancer, focusing on the regulation of chromatin structure dynamics (epigenomics) and chromatin remodeler protein complex assembly, as well as using genetic and chemical screens to identify potential therapeutic targets in human cancers.